Biotecnologia – Portugal

Advanced Courses CBMA-UM: Mammalian and yeast as complementary cell models in programmed cell death 17/06/2011

Filed under: Biotecnologia,Eventos — Hugo Azevedo @ 00:19

COORDINATORS       Manuela Côrte-Real, Maria João Sousa
CBMA-DB, Universidade do Minho, PORTUGAL
VENUE       Departamento de Biologia, Universidade do Minho
July 4-15
GENERAL INFORMATION       The course will include the theoretical modules referred above and a hands-on intensive module of lab work. In addition to brief descriptive lectures, the theoretical modules will entail case study and topic or problem–driven group discussions. The hands-on lab module will illustrate different aspects of the theoretical sessions topics, and will include different techniques to monitor morphological, biochemical and molecular changes associates to cell death processes namely, epifluorescence microscopy and flow cytometry. They will be followed by results interpretation, group discussion and final wrap up.
LECTURERS        Muriel Priault CNRS- Université de Bordeaux, France
Nadine Camougrand CNRS- Université de Bordeaux, France
Stéphen Manon CNRS- Université de Bordeaux, France
Campbell Gourlay Cell and Developmental Biology, Univeristy of Kent, UK 
M. Helena Vasconcelos Meehan Faculty of Pharmacy and IPATIMUP, University of Porto, Portugal
Ana Preto CBMA-DB, University of Minho, Portugal
Olga Coutinho CBMA-DB, University of Minho, Portugal
Manuela Côrte-Real CBMA-DB, University of Minho, Portugal
Maria João Sousa CBMA-DB, University of Minho, Portugal
  1. Programmed Cell Death processes versus necrosis
  2. Apoptosis
  3. Programmed necrosis
  4. Autophagy
  5. Autophagy in physiology and pathology
  6. Mitophagy: from yeasts to mammalian cells
  7. The central role of mitochondria in the intrinsic apoptotic pathway: mitochondrial membrane permeabilization mechanisms
  8. Apoptosis and the yeast actin cytoskeleton
  9. Utilization of yeast to study the molecular aspects of the function of Bcl-2 family members

10. A role for actin in regulating apoptosis/programmed cell death: evidence spanning yeast, plants and animals

11. Functional analysis of mammalian apoptotic proteins in yeast: screening for selective pharmacological modulators

12. Regulation of Bax by Mammalian Protein Kinase C

13. The role of human oncogene KRAS in autophagy regulation: Saccharomyces cerevisiae as a model

14. Features of Cell Death in Neurodegenerative Diseases

15. Regulation of Programmed Cell Death in Cancer and its Pharmacological Modulation

More Information


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